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A year-old man with AIDS presented with symptoms of a chronic cough, subacute headache, generalised weakness with falls, gesting and faecal incontinence, and acute onset subcutaneous nodules. A chest CT scan showed multiple cavitary and nodular pulmonary infiltrates.

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Pathological examination of the purulent material obtained from his subcutaneous lesions, as well as transbronchial tissue specimens obtained by biopsy, revealed beaded and branching Gram-positive rods, subsequently identified by 16S RNA sequencing to be Nocardia abscessus species. We observed an excellent therapeutic response to a combination antimicrobial therapy with resolution of the subcutaneous, pulmonary testjng central nervous system CNS lesions.

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Infections caused by N. In this article, we will review the presentation, diagnosis and treatment of N. Otherwise, individuals with medical conditions such as diabetes mellitus and those who use medications that suppress the immune system, including steroids, and transplant recipients, are similarly vulnerable to OIs.

Rarely, infections with NocardiaRheine county sluts and Aspergillus spp. Although the clinical syndromes associated with these organisms may be similar, differentiating between them is critically important as it affects the timely initiation of appropriate management fref determines patient outcomes.


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This case highlights the presentation and management of Nocardia infection, a disease which is uncommon among HIV-infected patients, partly due to the widespread use of sulfa-containing antibiotics for prophylaxis against OIs that have activity against the pathogen. In this article, we present a case of disseminated nocardiosis involving the CNS, lungs, and skin.

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